Fate of carbon skeletons. Metabolism of methionin, phenylalanine, tyrosine. Transmethylation reactions. Creatine metabolism

1. Which one of the following amino acids is ketogenic?

A. tyrosine;

B. tryptophan;

C. leucine;

D. isoleucine;

E. threonine.

2. All following amino acids are glycogenic and ketogenic, except …

A. tyrosine;

B. isoleucine;

C. tryptophan;

D. phenylalanine;

E. leucine.

3. In Parkinsonism patient has …

A. low level of GABA;

B. high level of serotonin;

C. high level of histamine;

D. low level of dopamine;

E. low level of melanin.

4. Branched chain amino acids are…

A. proline, alanine, serine;

B. alanine, cysteine, serine;

C. serine, threonine, tyrosine;

D. valine, leucine, isoleucine;

E. alanine, serine, valine.

5. Branched chain amino acids are used as…

A. sources of biosynthesis of biogenic amines;

B. sources of fuel for the heart and kidney;

C. sources of fuel for the brain;

D. substrates for gluconeogenesis;

E. substrates for ketogenesis.

6. Patients in Maple syrup disease have defect in….

A. homogentisate oxidase;

B. phenylalanine hydroxylase;

C. tyrosinase;

D. decarboxylase of branched chain keto acids;

E. decarboxylase of GABA.

7. Patients in albinism have defect in…

A. homogentisate oxidase;

B. phenylalanine hydroxylase;

C. tyrosinase;

D. decarboxylase of branched chain keto acids;

E. decarboxylase of GABA.

8. Patients in Alcaptonuria have defect in…

A. homogentisate oxidase;

B. phenylalanine hydroxylase;

C. tyrosinase;

D. decarboxylase of branched chain keto acids;

E. decarboxylase of GABA.

1. Patients in phenylketonuria have defect in…

A. homogentisate oxidase;

B. phenylalanine hydroxylase;

C. tyrosinase;

D. decarboxylase of branched chain keto acids;

E. decarboxylase of GABA.

10. Creatine kinase located in heart has following protomers…

A. MM;

B. HHHM;

C. BB;

D. MB;

E. HHHH.

PRACTICAL LESSON 5