Pathogenesis of High altitude disease

The causes The main (leading) pathogenetic factor CNS Cardiovascular system Respiratory system Blood system Skin Reduction in barometric pressure reduction рО2 in inhaled air ¯ hypoxemia ¯ metabolism disordersin ¯ glycolysis activation ¯ accumulation of lactic and piruvic acids ¯ acidosis ¯ lesions ¯ manifestations Euphoria, decreased mental proficiency, decreases judgment, memory and the performance of discrete motor movements, then depression of brain activity, disorders of movement coordination, convulsions and death. Tachycardia, cardiac output elevation, centralization of blood circulation Hyperpnea which is changed by bradypnea, then periodic breathing. Erythrocytosis Cyanosis   Change of physical properties of gases and liquids Decompression syndrome, meteorism, a pain in ears and frontal sinus, rupturing of microvessels, subcutaneous emphysema, gaseous embolism

№ 2.


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