Механизм действия

Hyman SE, Nestler EJ. Molecular foundations of psychiatry. Washington, DC: American Psychiatric Press, 1993.

Kapur S, Zipursky RB, Remington G. Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. Am J Psychiatry 1999; 156:286.

Nyberg S, Eriksson B, Oxenstierna G, et al. Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients. Am J Psychiatry 1999; 156:869.

Tamminga CA. Principles of the pharmacotherapy of schizophrenia. In: Charney DS, Nestler EJ, Bunnery BS, eds. Neurobiology of mental illness. New York: Oxford University Press, 1999.

Шизофрения и шизоаффективное расстройство.

American Psychiatric Association. Practice guidelines for the treatment of patients with schizophrenia. Am J Psychiatry 1997; 154 (4 suppl).

Breier A, Buchanan RW, Kirkpatrick B, et al. Effects of clozapine on positive and negative symptoms in outpatients with schizophrenia. Am J Psychiatry 1994; 151:20.

Carlsson A, Waters N, Carlsson ML. Neurotransmitter interactions in schizophrenia-therapeutic implications. Biol Psychiatry 1999; 46:1388.

Kane J, Honigfeld G, Singer J, et al. Clozapine for the treatment-refractory schizophrenic: a double-blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45:789.

Kane JM. Pharmacologic treatment of schizophrenia. Biol Psychiatry 1999; 46:1396.

Harder SR, Meibach RC. Risperidone in the treatment of schizophrenia. Am J Psychiatry 1994; 151:825.

Robinson DG, Woerner MG, Alvir JMJ, et al. Predictors of treatment response from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry 1999; 156:544.

Small JG, Hirsch SR, Arvanitis LA, et al. Quetiapine in patients with schizophrenia: a high- and low-dose double-blind comparison with placebo. Arch Gen Psychiatry 1997; 54:549.

Tollefson GD, Beasley CM, Tran PV, et al. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry 1997; 154:457.

Viguera AC, Baldessarini RJ, Hegarty JM, et al. Clinical risk following abrupt and gradual withdrawal of maintenance neuroleptic treatment. Arch Gen Psychiatry 1997; 54:49.

Аффективные расстройства.

Tohen M, Sanger TM, McElroy SL, et al. Olanzepine versus placebo in the treatment of acute mania. Am J Psychiatry 1999; 156:702.

Zarate СA, Tohen M, Baldessarini RJ. Clozapine in severe mood disorders. J Clin Psychiatry 1995; 56:411.


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