Individual work
Student of _________ group
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(name)
Lesson 10 (II). WATER-SOLUBLE VITAMINS.
1. Give a definition to term:
Vitamins – ___________________________________________________________________
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2. Give the examples of vitamins participating in:
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3. In what pathways of carbohydrates metabolism the vitamin B1 participates as a coenzyme of decarboxylases of a-keto acids? Write the examples of reactions.
1.
2.
4. What are the symptoms of vitamin В1 deficiency, and at what diet the requirement of vitamin B1 does increase?
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5. Fill in the table.
Vitamin | Usual name | daily dose, mg | The active group of coenzyme | The type of reactions, in which coenzyme is participating |
В1 | ||||
В2 | ||||
В3 | ||||
РР | ||||
В6 | ||||
Н | ||||
Вс | ||||
В12 | ||||
С |
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6. What are the symptoms of vitamin В2 deficiency?
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7. Indicate a correct answer. Deficiency of pantothenic acid at animals leads to development of dermatitises, lesions mucous, changes in heart and kidneys, depigmentation of hair, loss of appetite, neuritises, paralyses. What is the cause of this state?
A – insufficiency of respiratory enzymes;
B – change of activity of hydrolyzing enzymes;
C – insufficiency of coenzyme A;
D – insufficiency of lipase;
Е – insufficiency of enzymes of protein biosynthesis.
8. What is a biological role of vitamin РР, and what are the symptoms of its deficiency?
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9. What are the symptoms of В6deficiency В6, and at what diet the requirement of vitamin B6 does increase? _____________________________________________________________________
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10. What vitamin is synthesized in the animal organism from tryptophan?_____________________
11. Indicate a correct answer. In what processes the biotin DOES NOT participate?
А – biosynthesis of fatty acids;
В – biosynthesis of purine;
С – gluconeogenesis;
D – biosynthesis of glycogen;
Е – oxidation of residue of propionic acid in a Krebs cycle.
12. What is the chemical nature of internal factor necessary for absorption of vitamin B12? ____________________________________________________________________________
13. Write the formula and name the active form of folic acid.
14. What are the symptoms of deficiency of vitamin Bс?
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15. Write names of diseases, symptoms of which are figured at pictures. From the biochemical point of view explain the causes of their development.
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2. ____________________________________________________
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3. ____________________________________________________
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16.1. In the patient with decreased gastric acidity and disorders of nervous system the physician has suggested the hypovitaminosis В12 and administrated blood analysis. Indicate the significances of erythrocytes and hemoglobin values, which can confirm this diagnosis.
Erythrocytes –
Hemoglobin –
16.2. What will be observed: normochromia, hypochromia, hyperchromia (underline)? What cells, non-characteristic for healthy persons, it is possible to find in the blood and bone marrow of this patient? ________________________________________________________________
16.3. What is more possible reason for the hypovitaminosis В12 in this patient? How it is necessary to take vitamin for treatment? __________________________________________________
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