Practical lesson 2

CONVERSION OF α- AMINO GROUP. DISPOSAL AND DETOXIFICATION OF AMMONIA. CONVERSION FOR α- CARBOXYL GROUP

Choose the correct answer:

1. The cofactor of amino transferases is…

A. TDP;

B. FAD or FMN;

C. NAD⁺ or NADP⁺;

D. PLP;

E. biotin.

2. The most frequently as acceptor for α-amino group … is used.

A. pyruvic acid;

B. oxaloacetate;

C. α-ketoglutarate;

D. aspartate;

E. glutamic amino acid.

3. Glutamate DH is available only in the…

A. liver;

B. kidney;

C. brain;

D. muscle;

E. lung.

4. Molecule trapping ammonia in brain is…

A. pyruvic acid;

B. oxaloacetate;

C. glutamic acid;

D. asparagine;

E. glutamine.

5. Transport form of ammonia from brain to liver is…

A. alanine;

B. glutamic acid;

C. aspartic acid;

D. glutamine;

E. all answers are correct.

6. Transport form of ammonia from muscle to liver is…

A. alanine;

B. glutamic acid;

C. asparagine;

D. glutamine;

E. all answers are correct.

7. Rate-limiting step in urea formation is…

A. carbomoyl phosphate synthetase reaction;

B. ornithine trans carbomoylase reaction;

C. argininosuccinate synthetase reaction;

D. argininosuccinate lyase reaction;

E. arginase reaction.

8. The cofactor of decarboxylases is…

A. NAD⁺;

B. NADP⁺;

C. FAD;

D. FMN;

E. PLP.

9. Allergic reactions can be connected with high levels of …

A. GABA and serotonin;

B. serotonin and histamine;

C. histamine and dopamine;

D. dopamine and GABA;

E. GABA and histamine.

10.In brain tissue as an inhibitory neurotransmitter …. is used.

A. serotonin;

B. histamine;

C. dopamine;

D. GABA;

E. melatonin.

PRACTICAL LESSON 3