For thyrotoxicosis, the following set of symptoms is characteristic: (3)

The correct variant of cerebropituitary regulation of the endocrine glands: (1)

1 the cerebral cortex is the peripheral gland.

2 cortex - hypothalamus-pituitary gland - peripheral gland.

3 the cerebral cortex - the hypothalamus - nerve conductors - peripheral glands.

4 cortex - pituitary gland - hypothalamus - peripheral gland.

5 subcortical centers - nerve conduits - peripheral gland

 

Transhypophysial regulation is fundamental to: (3)

1. pancreas

2. thyroid gland

3. gonads

4. parathyroid glands

5. adrenal cortex

                                 

Hormone metabolism is impaired in diseases of: (1)

1 liver

3 the spleen

3 hearts

4 lungs

5 nervous system

 

Peripheral (non-glandular) mechanism of hormone activity disturbance is: (1)

  1 Deficiency of substrates for the formation of hormones.

2 Inherited defect of hormone biosynthesis enzymes.

3 Adenoma of the neurosecretory cells of the hypothalamus.

4 Congenital malformations of the glands.

5 Blockade of hormonal receptors.

With eosinophilic pituitary adenoma, during the growth period of the body, it develops: (1)

1 acromegaly;

2 gigantism;

3 dysplasia;

4 pituitary dwarfism;

5 Itsenko-Cushing's disease.

 

A decrease in the production of adrenocorticotropic hormone leads to: (1)

1 a decrease in insulin synthesis

2 decrease the synthesis of hormones of the adrenal cortex

3 decrease the synthesis of hormones of the adrenal medulla

4 increased synthesis of thyroid hormones

5 increased synthesis of sex hormones

 

Excessive production of adrenocorticotropic hormone leads to increased secretion: (1)

1 insulin

2 parathyroid hormone.

3 thyroxine.

4 cortisol.

 

Hypoproduction of growth hormone at a young age manifests itself in the form: (1)

1. acromegaly

2. pituitary cachexia

3. adiposogenital dystrophy

4. pituitary gigantism

5. pituitary dwarfism

 

The development of diabetes insipidus is due to: (1)

1. hypersecretion of vasopressin

2. hyposecretion of vasopressin

3. hypersecretion of aldosterone

4. hypersecretion of aldosterone

5. the presence of insulin antagonists in the blood

 

The cause of Addison's disease is most often: (1)

1. hypertrophy of the adrenal glands

2. adrenal atrophy

3. pituitary tumor

4. autoimmune thyroiditis

5. pineal gland hyperplasia     

 

With insufficient iodine in food develops: (1)

1. autoimmune thyroiditis;

2. hyperthyroidism;

3. hypoparathyroidism;

4. endemic goiter;

5. diffuse toxic goiter.

 

 

In severe cases, hypothyroidism in adults provides development: (1)

1 cretinism

2 myxedema

3 eunuchoidism

4 dwarf dwarfism

5 hypergonadism

 

Hypoparathyroidism occurs with pathology: (1)

1 gonads

2 thyroid gland

3 parathyroid glands

4 thymus gland

5 pancreas

 

 14. Which endocrine disorder is defined as secondary/tertiary? (2)

1. Pathological process in a certain endocrine gland

2. It is a result of an increased releasing factors level

3. It is a result of an impaired tropic hormones regulation

4. It is a result of genetic defect in the gland

 

Tachycardia in hyperthyroidism is a result of: (1)

1. Blocked parasympathetic activation

2. Increased cardiac afterload

3. Decreased cardiac preload

4. Increased sympathetic activation

5. Malignant hyperthermia

 

The pathogenesis of chronic hypocorticism is associated with decreased levels of: (2)

1. GCS

2. MCS

3. Suprarenal sex hormones

4. Catecholamines

 

The biological effects of STH could be diminished in a deficiency of: (1)

1. Somatostatins

2. Somatoliberins

3. Somatomedins

4. Prostaglandins

5. Leukotriens

 

What is the cause of primary diabetes insipidus?

1. Damage in the hypothalamus and hypophysis

2. Hereditary defect of the ADH receptors in the renal tubules

3. Acquired defect of the ADH receptors in the renal tubules

4. Hyperplasia of the epiphysis

5. Atrophy in substantia nigra

 

Pheochromocytoma leads to: (1)

1. Elevated catecholamines

2. Elevated aldosterone

3. Increased level of tropic hormones

4. Decreased level of catecholamines

5. Overactivated parasympathetic nervous system

 

In primary hyperaldosteronism: (1)

1. Aldosterone does not affect renin secretion

2. There is increased level of aldosterone and increased level of renin

3. There is decreased level of aldosterone and decreased level of renin

4. There is increased level of aldosterone and decreased level of renin

5. Aldosterone augments the circadian rhythm of renin secretion

 

What signs are characteristic of severe hypothyroidism in adults? (5)

1. Obesity

2. Sweating

3. Slowed intellectual and motor activity

4. Arterial hypertension

Cool skin, cold intolerance

Fatigue

7. Tachycardia

8. Hypercholesterolemia

Indicate the possible causes of hyperthyroidism: (6)

1. The lack of thyroliberin

2. Excess TSH

3. Excess immunoglobulins TS-Ig (LATS)

4. Thyroiditis

5. Thyroid adenoma

6. Weak transport connection with blood proteins

7. Intensive conversion of T4 to T3 in ‘target’ cells

8. The increase in the number of receptors T3, T4

Is it true that hyperthyroidism can be autoimmune?

1. Yes

2. No

Indicate the main manifestations of hyperthyroidism: (6)

1. Increased basal metabolic rate

2. The tendency to hyperthermia

3. Bradycardia

4. Nervousness

5. Hypoglycemia

6. Hypercholesterolemia

7. Systolic hypertension

8. Weight loss

9. Intolerance and sweating warm

Indicate the possible causes of hypothyroidism: (5)

1. Excess ACTH

2. Excess thyroliberin

3. Iodine deficiency

4. Toxic blockade of iodine uptake and tyrosine compounds

5. Surgical or radioiodine ablation of the thyroid gland

6. Autoimmune thyroiditis

7. Immunoglobulin deficiency

8. Circulating cytotoxic antithyroid antibodies

The phenomenon of Wolff-Chaikoff is characterized by: (1)

1. The development of hyperthyroidism in response to an increase in iodine intake

2. The development of hypothyroidism in response to an increase in iodine intake

3. The development of hyperthyroidism in response to a decrease in iodine intake

4. The development of hypothyroidism in response to a decrease in iodine postulation in the body

For thyrotoxicosis, the following set of symptoms is characteristic: (3)

1. Exophthalmos, cold skin, tachycardia

2. Periorbital edema, tachycardia, muscle weakness

3. Exophthalmos, tachycardia, increased basal metabolic rate

4. Inhibition, hot skin, hypotension

5. Sweating, fine tremor, shaky handwriting, clumsiness

6. Hyperthermia, constipation, memory loss

7. Hyperthermia, diarrhea, arterial hypertension