ANABOLISM OF LIPIDS. METABOLISM OF KETONE BODIES
Choose the correct answer:
1. Common precursors for synthesis of TG and PL are following except
A. glycerol 3 phosphate;
B. acyl CoA;
C. phosphatidic acid;
D. dioxyaceton phosphate;
E. citidyldiphosphorylglycerol.
2. For biosynthesis of palmitate needs following except
A. acetyl CoA;
B. NADPHH+;
C. CO2 and ATP;
D. biotin;
E. vitamin C.
3. Enzymes participating for synthesis of palmitate are following except
A. isocitrate DH (in mitochondria);
B. citrate synthase;
C. malic enzyme;
D. acyl CoA carboxylase;
E. fatty acid synthase complex.
4. The reduction of NADP+ takes place in the following reactions and pathway. Choose one in correct answer
A.PPP;
B.HMP shunt;
C. “malic” reaction;
D. isocitrate DH reaction (cytosolic);
E. isocitrate DH reaction (mitochondria).
5.The key enzyme of fatty acid synthesis is…
A. citrate lyase;
B. acetyl CoA carboxylase;
C.3-ketoacyl synthase;
D.3-ketoacyl reductase;
E. β-hydroxy-β-metylglutaryl reductase.
6. Activator for fatty acid synthesis is…
A. adrenalin;
B. noradrenalin;
C. glucagon;
D. insulin;
E. cAMP
7. Acyl CoA carboxylase in…
A. mitochondria;
B. cytosol;
C. endoplasmic reticulum;
D. liposome;
E. microsome.
8. Fatty acid synthase complex in….
A. mitochondria;
B. cytosol;
C. endoplasmic reticulum;
D. liposome;
E. microsome.
9. Which one of the following statement about fatty acid synthase is in correct.
A. in human body synthase exists as a dimer;
B. synthase complex contains of 7 enzymes;
C. as source of reduced equivalent NADPHH+ is used;
D. location in cytosol;
E. needs for biotin
10. Shuttle system participating in the synthesis of fatty acid is…
A. malate-aspartate;
B. glycerophosphate;
C. malate.
D. citrate;
E. carnitine
PRACTICAL LESSON 3