Case 5

Surgery of a patient is performed with the use of mechanical ventilation. Describe the violation of ABB of the patient. Explain the pathogenesis of changes.
pH 7.24
pCO2 69 mm Hg. Art.
SB 18,5 mmol / l
AB 28.0 mmol / l
BE -8.0 mmol / l

Questions:

1. Rate the pH of arterial blood, indicate its degree (compensated, decompensated)
2. Make a conclusion about a type of ABB, justify the answer
3. Rate the value of indicators of ABB. What is the cause of AB disorders
4. Explain compensatory mechanisms of ABB disorders of the patient

Hand-outs: cases, lecture, multimedia presentation

7.7.6. THE LIST OF LITERATURE:

The basic

4. Litvitsky P.F., Pirozhkov S.V., Tezikov E.B. Concise lectures and tests on pathophysiology E-tekstbook. – ГЭОТАР-Медиа, 2007

Additional

5. Textbook of pathology. Harsh Mohan. Body fluid and circulatory disturbances. 4rd edition, Delhi, 2004.- P 100-102.

6. Textbook of medical physiology. Regulation of acid-base balance. A.C. Guyton, J.E. Hall., 9^th edition, 1996.-P. 385-403

6.2.7. The purposes of the class:

· Formation of knowledge of the main issues of the theme

· Formation of skills of analysis of experimental data and creation of pathogenetic schemes

· Formation of communicative skills for discussion of the problem

6.3.7. Tasks of study:
• To learn the main issues of the theme
• To develop the skills to use the glossary in three languages for discussion theoretical material
• To Learn how to make pathogenetic schemes
• To apply the theoretical knowledge in solving clinical cases

• To form communicative skills for discussion the theoretical material
6.4.7. Questions for the theme

1. Disorders of glycogen synthesis and disintegration. Concept about glycogenoses.

2. Disorders of intermediate metabolism of carbohydrates (hyperlactatacidemia, hyperpiruvatacidemia), pathogenesis.

3. Hypoglycemia, the causes. Pathogenesis of hypoglycemic coma.

4. Hyperglycemia, types, mechanisms of development.

5. Pancreatic and nonpancreatic insulin insufficiency, mechanisms of development. Concept about type I diabetes and type II diabetes.

6. Metabolism disorders at diabetes mellitus.

7. Pathogenesis of the symptoms of diabetic syndrome, pathogenesis of diabetic coma.

8. Complications of diabetes mellitus. Pathogenesis of micro-and macroangiopathy. Pathogenesis of micro-and macroangiopathy