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Applies to vitamin e: compounding powder, oral capsule, oral liquid, oral solution, oral tablet, oral tablet chewable

Gastrointestinal

Gastrointestinal side effects associated with oral doses greater than 300 units daily have rarely included nausea, diarrhea, and intestinal cramps.[Ref]

Other

Other side effects associated with oral doses greater than 300 units daily have rarely included fatigue, emotional disturbances, weakness, and headache.[Ref]

Hematologic

Hematologic side effects associated with oral doses greater than 300 units daily have rarely included thrombophlebitis.[Ref]

Ocular

Ocular side effects associated with oral doses greater than 300 units daily have rarely included blurred vision.[Ref]

Dermatologic

Dermatologic side effects associated with oral doses greater than 300 units daily have rarely included rash.

Dermatologic side effects associated with topical application of vitamin E have included growth of white hair at site of alopecia and contact dermatitis.[Ref]

Genitourinary

Genitourinary side effects associated with oral doses greater than 300 units daily have rarely included gonadal dysfunction and breast soreness.[Ref]

Endocrine

Endocrine side effects associated with oral doses greater than 300 units daily have rarely included decrease in serum thyroxine and triiodothyronine.[Ref]

Metabolic

Metabolic side effects associated with oral doses greater than 300 units daily have rarely included creatinuria, increased serum creatinine kinase, increased serum cholesterol and triglycerides and increased urinary estrogens and androgens

Vitamin e Pregnancy Warnings

Vitamin E has been assigned to pregnancy category A by the FDA when used in doses that are advocated by the FDA. Doses exceeding the recommended dietary allowance(RDA) have been assigned to pregnancy category C. Animal studies have not been reported. There are no controlled data in human pregnancy. Vitamin E is only recommended for use during pregnancy if clearly needed and then only when benefit outweighs risk.

Vitamin e Breastfeeding Warnings