Ф КГМУ 4/3-05/03
ИП №6 от 14 июня 2007 г.
KARAGANDA STATE MEDICAL UNIVERSITY
Department: PHYSIOLOGY
Methodical recommendations for practice lessons
Topic: «External respiration»
Specialty «General medicine» 051301
Discipline: «Physiology-2»
Course: 3
Compliers: Аss. Of prof. N.M. Kharrisova
Karaganda
Discussed and confirmed at the meeting of the Department of Physiology
Protocol № _____ of _________.2014
Head of the Department, Professor _______________ F.A.Mindubaeva
Topic: «External respiration»
Purpose: to master physiological methods for studying external respiration parameters, to study the mechanisms of inspiration and expiration, maintaining constant gas composition of the blood.
Educational objectives:
o To use the theoretical knowledge into practice during the work and analysis of the results
o at performance of works to continue formation scientific research competence.
Basic questions of the topic
1 The concept about the respiratory system, its functions.
2 The Breathing. Respiratory cycle. The main stages of respiration.
3 Functions of the lungs and airways (gas exchange and nogas exchange).
4 The importance of surfactant.
5 The pressure in the pleural cavity, its origin.
6 Mechanism of inspiration. inhalation
7 The mechanism of exhalation.
8 The lung volumes and capacities. Methods of study of external respiration (pneumography, spirography, spirometry, pneumotachometry).
9 The Quantitative indicators of ventilation (maximal voluntary ventilation (MVV,) low voluntary ventilation (LVV).
Educational methods: mastering clinical and physiological methods for studying external respiration, small group work, oral questioning, testing, solution of case studies, discussion, discussion of the results of the study.
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The list of performed works.
WORK 1. Spirography at rest by spirometer Sriros-100
Objective: To familiarize yourself with the principle of the spirometer Spiro C-100. To be able to make a graphic recording of respiratory volumes at rest.
Course of the work: see Instructions in the work of spirometry C-100
Conclusion: to draw the resulting curve, make the appropriate notation.
Lung volumes and capacities | Method of definition | Result |
VLC Vital Capacity | VLC= | |
RV (respiratory volume) | RV= | |
Capacity of inspiration | CI=RV+RVI | CI= |
Reserve volume of inspiration | РО вдоха= ЖЕЛ – (ДО + РО выдоха) RVI=VLC-(RV+RVE) | RVI= |
Reserve volume of exspiration | RVE= |
Work 2: Determination of pulmonary ventilation and low voluntary ventilation (LVV)
Objective: To assess pulmonary ventilation (tidal volume – TV) during quiet breathing and calculate minute volume of respiration (low voluntary ventilation - LVV), which reflects the performance of the lungs.
Course of the work: Determine using spirometer tidal volume (TV) during quiet breathing.
Count the number of breaths in 1 minute during quiet breathing (respiration rate - RR).
Calculate minute volume of respiration (low voluntary ventilation) (LVV) by the formula:
LVV =RR * TV
Calculate the alveolar ventilation (AV) by the formula:
AV = RR*(TV-DS) = RR*TV- RR*DS =LVV - (RR * DS)
ИТ = ОФВ1/ЖЕЛ (FEV1/VC = Index Tiffeneau) - индекс Тиффно |
ИГ = ОФВ1/ФЖЕЛ (FEV1/FVC = Index Gaenslar) - индекс Генслара |
DS- Dead Space - (150ml)