Неправильный вариант: This is an unpleasant moment, which we will have to take into account.
Правильные варианты: This is a difficulty / problem / annoyance / irritant which we will have to take into account / with which we will have to cope / contend / which we will have to face.
Спад цен на эти акции – неприятный момент для нашей фирмы.
Неправильный вариант: The fall of the prices on these stocks is in unpleasant moment for our firm.
Правильный вариант: The decline / drop in the prices of these stocks is causing problems / difficulties / is a negative factor for our firm.